JSG-100立式干法制粒機(jī)工作原理(Working Theory of Dry TypeGranulation Facility):
根據(jù)機(jī)械擠壓造粒工藝原理,將配置好的,具有一定結(jié)晶水的干粉狀或微細(xì)晶體狀原料,擠壓成薄片,后經(jīng)造粒系統(tǒng),通過篩網(wǎng)制成所需大小的顆粒。
原料可通過手工上料或真空上料機(jī)加入料斗,經(jīng)送料螺桿輸送和壓縮.被推至兩擠壓輥輪的咬入角:通過壓輥,將原料擠壓成薄片。物料所需的壓力通過液壓裝置線性傳送給壓輥,液壓裝置可保持一定的預(yù)壓力, 垂直排列的壓輥可保證物料密度的一致性。根據(jù)不同顆粒度要求,設(shè)備造粒系統(tǒng)中的篩網(wǎng)目數(shù)大小可相互更換。
According to the technical theory ofmechanical extrusion for granulation, a wel-prepared powdery or finely crystallinematerial with crystal water is laminatedand made into particles of required size bymeans of screen in the granulation system.
The material may be fed into the bucketby hand or vacuum feeder, conveyed andcompressed in the feed screw, and pushedinto bite angle of two extrusion wheels.The material is laminated by therollers.The pressure required by material islinearly delivered from hydraulic device torollers. The hydraulic device can maintaincertain pre-pressure and the verticallyarranged rollers can guarantee theconsistent density of According to different required grainmaterial.sizes, the screens with different meshes inthe granulation system can be interchanged.
JSG-100立式干法制粒機(jī)干法制粒優(yōu)點(diǎn)(Advantages of Dry TypeGranulation):
將粉體或微細(xì)晶體原材料直接制成滿足用戶要求的顆粒狀產(chǎn)品,無需任何中間體和添加劑,造粒后產(chǎn)品粒度均勻,堆積密度顯著增加,改善流動(dòng)性,既控制'了粉塵飛揚(yáng),又減少粉料浪費(fèi)。便于貯存和運(yùn)輸,可控制溶解度、孔隙率和比表面積等。
本機(jī)在濕式造粒法中難生產(chǎn)的抗生物質(zhì)。膠囊填充用顆粒及制造藥片的造粒上能發(fā)揮很大的作用。
Powder or fine crystal can be directlymade into granules to the satisfaction ofusers, without requiring any intermediate oradditive. The granules have even grain sizewith considerably increasing bulk density.This can improve the fluidity, inhibit theraised dust and reduce the waste of powder.
It is easy to store and transport andallows the control of solubility, porosity andspecific surface area.The granulator generates the antibioticThe granulator generates the antibiotictype granulation. .type granulation. .It can play an importantrolein thein thethe granulation for pills.
JSG-100立式干法制粒機(jī)應(yīng)用范圍(Applcability):
在制藥工業(yè)中,廣泛涉及到對(duì)各種活性的藥品原料以及-種或多種賦形劑的加工處理。這些原料藥大部分是細(xì)的粉末,并且這些粉末粒徑大小不一,密度不勻,流動(dòng)性差,易分層。這些原料藥必須經(jīng)過制粒工藝處理.才能.被用于壓片、膠囊填充或其他藥物加工工序。干法制粒因其具有多種優(yōu)勢(shì).特別適用于在濕.熱條件下不穩(wěn)定的藥物的制粒。
The pharmaceutical industry oftenprocesses the medicine materials of variousactivities and one or several excipients.Most of bulk drugs are finely powdery indifferent grain sizes, uneven density, poorfluidity and easy stratification. They must begranulated before being laminated, flled intocapsules or processed in other ways. Forits various advantages, dry type granulationis particularly suitable for the granulation ofdrugs unstable under wet and hot conditions.
JSG-100立式干法制粒機(jī)特別說明(Special Note):
在產(chǎn)品設(shè)計(jì)和生產(chǎn)過程中,我們遵循了美國FDA、GMP思想。任何一臺(tái)設(shè)備在生產(chǎn)過程中,皆具備GMP控制范圍;在設(shè)計(jì)過程中,任何一臺(tái)設(shè)備皆在GMP內(nèi)創(chuàng)新構(gòu)思。所有的非金屬材料均符合GMP &FDA標(biāo)準(zhǔn)。
送料量、壓力、壓輥間隙、片厚、整粒間.隙、片硬度等工藝參數(shù)通過邏輯運(yùn)算、數(shù)理統(tǒng)計(jì)建數(shù)據(jù)模型,并形成科學(xué)系統(tǒng)關(guān)系。
In the machine design and .manufacturing process, we follow theFDA GMP idea. Any equipment in themanufacturing process has GMP controlrange,In the designing process, anyequipment is in GMP innovation concept.All non-metallic materials comply withGMP&FDA standards.
The process parameters such as feedamount,pressure roller gap, slicethickness,grinding gap and slice .hardness were established to formscientific system relationship throughlogical operation and mathematicalstatistics.
JSG-100立式干法制粒機(jī)設(shè)計(jì)特點(diǎn)(Design Features):
1、壓輪及壓輪座為外露式結(jié)構(gòu)設(shè)計(jì);
2、工藝處理裝置可快速拆卸,以便生產(chǎn)設(shè)施外進(jìn)行清潔和滅菌處理;
3、制粒過程在精密的制粒裝置中完成,先進(jìn)的制粒系統(tǒng).獨(dú)特的制粒構(gòu)造設(shè)計(jì),使生產(chǎn)成品率大大提高.減少了二次回料加工.提高生產(chǎn)產(chǎn)品質(zhì)量與產(chǎn)量;
4、生產(chǎn)過程的控制和確認(rèn)可通過PLC操作程序執(zhí)行或手工操作控制執(zhí)行完成;
5、壓輪表面經(jīng)氣體滲氮處理,具有較強(qiáng)的耐磨性和抗疲勞強(qiáng)度,且具有較好的抗腐蝕性;
6、側(cè)密封板通過絲桿定位調(diào)節(jié),延長(zhǎng)側(cè)密封板的使用壽命;
7、整機(jī)自帶水冷卻循環(huán)系統(tǒng),保證壓輪在使用過程中的溫度得到控制.防止物料在壓制過程中因受熱而粘結(jié)、變色.變質(zhì);
8、液壓系統(tǒng)通過電控調(diào)節(jié)控制.無需手動(dòng)開啟壓力表開關(guān)操作;
9、根據(jù)物料特性。選擇壓縮軋輥與送料螺桿得到分布均勻顆粒;
10、作業(yè)性.安全性優(yōu)越,可符合GMP要求;
11、無需添加潤(rùn)滑劑.也能成型;
12、振蕩功能設(shè)計(jì).防止物料吸附.增強(qiáng)物料流動(dòng)性;
13、打印功能設(shè)計(jì).便于打印不同配方顆粒數(shù)據(jù)及類別區(qū)分。
1、Pressing wheel and its base are designedin anexposed structure;
2、The processing device can be rapidlydetached to facilitate the cleaning andgermicidal treatment outside the faciliy;
3、The process of granulation is completedin the delicate granulation facility. Theadvanced granulation system and uniquegranulation design considerably improvethe rate of finished products, reducethe processing of recycled material andenhance the quality and yield of products;
4、The control and verification of productionprocess can be performed by PLC .operating program or manually;
5、The pressing wheel surface receivesthe gas nitriding treatment to obtain highwearing quality and fatigue resistance aswell as good anticorrosion;
6、Side sealing board is positioned andmodulated by screw to elongate itsservice life;
7、The unit is equipped with water coolingcirculation system to guarantee thetemperature of pressing wheel undermaterial from caking, discoloringand deterioration in the process ofcompression.
8、The hydraulic system is manipulatedelectrically without manually turning onpressure gauge.
9、The hydraulic system is manipulated letrially withoutmanually turmning on pressure gauge.
10、The compression roller and feed screw are selectedaccording to the nature of material to evenly distrbutethe granules;
11、The operation perormance and safety are outstandingand meet the GMP requirements;
12、Forming can be performed without adding lubricant;
13、The design of oscillation can prevent the absorption ofmaterial and increase the fluidity of material.
JSG-100立式干法制粒機(jī)技術(shù)參數(shù)(Technical Parameters):
生產(chǎn)能力
●生產(chǎn)處理量: 100Kg/h (以食用玉米淀粉為例)
●可成型粒度: 0.2-2 mm(更換篩網(wǎng)調(diào)節(jié))
● 油泵:電動(dòng)加壓;
●成型壓力: 40T
● 安裝功率: 12.5KW
●整機(jī)重量: 1600kg
●外形尺寸:1250x1230x2250(mm)
●壓輪大小: 208x78 (mm)
●料架升降:液壓升降
●物料接觸部分材質(zhì):SUS 304 &316L
●擠壓輪材質(zhì):2Cr13、3Cr13、合金鋼
●與產(chǎn)品接觸的徑向軸密封圈: PTFE/氟橡膠
●Production capacit: 100kg/h (dependingon the nature of material)
●Grain size: 0.2-2mm
●Oil pump: electrical
●Maximum forming pressure: 40T
●Installation power:12.5KW
●Dead weight: 1600kg
●Dimension:1250x1230x2250(mm)
●Size of pressing wheel:208x78(mm)
●Rack elevation: hydraulic
●Material: SUS 304 & 316L
●Material of roller: 2Cr13、 3Cr13、 alloy steel
●Axial gasket in contact with product:PTEF/fluorubber